Self-assembled cGAMP-STINGΔTM signaling complex as a bioinspired platform for cGAMP delivery

Abstract

A bioinspired approach was developed for STING agonist delivery with STINGΔTM as a functional carrier.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jun 12, 2020
Source ID
10.1126/sciadv.aba7589

Entities

People

  • Celestine Hong
  • Darrell J Irvine
  • Emily Z Yan
  • Ge Zhu
  • Jiahe Li
  • Mengdi Yang
  • Paula T. Hammond
  • Samantha J. Fletcher
  • Xin Sun
  • Yanpu He
  • Yingzhong Li

Organizations

  • Howard Hughes Medical Institute
  • Massachusetts Institute of Technology
  • Northeastern University
  • United States Department of Defense

Tags

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech