Critical role of synovial tissue–resident macrophage niche in joint homeostasis and suppression of chronic inflammation

Abstract

Using a novel model of rheumatoid arthritis, we identified a critical role for reduced tissue-resident macrophages.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 08, 2021
Source ID
10.1126/sciadv.abd0515

Entities

People

  • Alexander V. Misharin
  • Debbie Winter
  • Qi-Quan Huang
  • Qicong Sheng
  • Qinwen Mao
  • Renee Doyle
  • Richard M. Pope
  • Shang-Yang Chen

Organizations

  • American College of Rheumatology
  • American Federation for Aging Research
  • American Heart Association
  • American Lung Association
  • National Research Foundation
  • Northwestern University
  • Office of the Director
  • Scleroderma Foundation
  • United States Department of Defense

Tags

Fields of Study

  • Medicine