Human physiomimetic model integrating microphysiological systems of the gut, liver, and brain for studies of neurodegenerative diseases

Abstract

Engineered model of the human gut-liver-brain axis can be used to study the link between the microbiome and Parkinson’s disease.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 29, 2021
Source ID
10.1126/sciadv.abd1707

Entities

People

  • Attya Omer
  • Austin Hendricks
  • Catherine Communal
  • Charles W. Wright
  • David L. Trumper
  • Devon Svoboda
  • Douglas A. Lauffenburger
  • Emile Wogram
  • Jason Velazquez
  • Julien Muffat
  • Kirsten Schneider
  • Linda Griffith
  • Martin Trapecar
  • Meelim Jasmine Lee
  • Pierre Sphabmixay
  • Rudolf Jaenisch
  • Samuel Mildrum
  • Stuart S Levine
  • Tenzin Lungjangwa

Organizations

  • Army Research Office
  • Korea National Institute of Health
  • Massachusetts Institute of Technology
  • National Cancer Institute
  • National Institute of Environmental Health Sciences
  • Whitehead Institute

Tags

Fields of Study

  • Biology

Readers

  • Microbial Pathology
  • Molecular and Cellular Biology