Adipose saturation reduces lipotoxic systemic inflammation and explains the obesity paradox

Abstract

Saturated fat breaks down less during sudden illnesses, resulting in lower monomer concentrations, and reducing disease severity.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 29, 2021
Source ID
10.1126/sciadv.abd6449

Entities

People

  • Andre Guerra
  • Bara El-kurdi
  • Biswajit Khatua
  • Christopher Rood
  • Douglas O Faigel
  • Jordan R Yaron
  • Krutika Patel
  • Mark E Lowe
  • Michael Crowell
  • Pawan Noel
  • Sergiy Kostenko
  • Vijay P Singh

Organizations

  • Mayo Clinic
  • National Institute of Diabetes and Digestive and Kidney Diseases
  • Saint Louis University
  • United States Department of Defense
  • Washington University in St. Louis

Tags

Readers

  • Exercise and Sports Science.
  • Immunology and Pathology
  • Mathematics or Statistics