Synthetic auxotrophy remains stable after continuous evolution and in coculture with mammalian cells

Abstract

A synthetic auxotroph does not escape from biocontainment after evolution, demonstrating that life does not always find a way.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jul 02, 2021
Source ID
10.1126/sciadv.abf5851

Entities

People

  • Aditya M Kunjapur
  • Daniel J. Mandell
  • Eriona Hysolli
  • Evan Appleton
  • George M. Church
  • Karen Noguera
  • Max G. Schubert
  • Michael G. Napolitano
  • Michaela A. Jones
  • Siddharth Iyer

Organizations

  • Army Research Office
  • General Medical Council
  • Harvard Medical School
  • National Institute of General Medical Sciences
  • National Science Foundation
  • United States Department of Energy
  • University of Delaware

Tags

Fields of Study

  • Biology