Topological tuning of DNA mobility in entangled solutions of supercoiled plasmids
Abstract
Simulations and microscopy show that supercoiling enhances the dynamics of DNA by reducing threadings and entanglements.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- May 14, 2021
- Source ID
- 10.1126/sciadv.abf9260
Entities
People
- Davide Michieletto
- Jan Smrek
- Jonathan Garamella
- Rae Robertson-Anderson
Organizations
- Air Force Office of Scientific Research
- Austrian Science Fund
- Leverhulme Trust
- University of Edinburgh
- University of San Diego
- University of Vienna