Designed, highly expressing, thermostable dengue virus 2 envelope protein dimers elicit quaternary epitope antibodies
Abstract
A stabilized dimer of the surface protein from dengue virus has been engineered to elicit antibodies that neutralize the virus.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Oct 15, 2021
- Source ID
- 10.1126/sciadv.abg4084
Entities
People
- Alexander M. Payne
- Aravinda M. de Silva
- Ashutosh Tripathy
- Brian Kuhlman
- Devina Thiono
- Gregory D. Gromowski
- Ian Seim
- Jack B. Maguire
- Joseph S. Harrison
- Lakshmanane Premkumar
- Lawrence Forsberg
- Michael K McCracken
- Nathan I Nicely
- Richard G Jarman
- Sandrine Soman
- Shaomin Tian
- Shu Zhang
- Stefan W Metz
- Stephan T. Kudlacek
- Thanh T. N. Phan
Organizations
- University of North Carolina
- Walter Reed Army Institute of Research