Multiform antimicrobial resistance from a metabolic mutation

Abstract

Disruption of a metabolic pathway causes tolerance, high persistence, and MIC-shifted resistance to diverse antibiotics.

Document Details

• Document Type: Pub Defense Publication
• Publication Date: Aug 27, 2021
• Source ID: 10.1126/sciadv.abh2037

Entities

People

• Carl F. Nathan
• Hélène Botella
• Julien Vaubourgeix
• Kyu Y Rhee
• Robert S Jansen
• Sabine Ehrt
• Sarah M Schrader

Organizations

• Imperial College London
• National Institute of Allergy and Infectious Diseases
• National Institute of General Medical Sciences
• Radboud University Nijmegen
• United States Department of Defense
• Weill Cornell Medicine