Genome Sequence of the Radioresistant Bacterium Deinococcus radiodurans R1
Abstract
The complete genome sequence of the radiation-resistant bacterium Deinococcus radiodurans R1 is composed of two chromosomes (2,648,638 and 412,348 base pairs), a megaplasmid (177,466 base pairs), and a small plasmid (45,704 base pairs), yielding a total genome of 3,284,156 base pairs. Multiple components distributed on the chromosomes and megaplasmid that contribute to the ability of D. radiodurans to survive under conditions of starvation, oxidative stress, and high amounts of DNA damage were identified. Deinococcus radiodurans represents an organism in which all systems for DNA repair, DNA damage export, desiccation and starvation recovery, and genetic redundancy are present in one cell.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Nov 19, 1999
- Source ID
- 10.1126/science.286.5444.1571
Entities
People
- Celeste Zalewski
- Claire M. Fraser
- Daniel H. Haft
- Delwood L. Richardson
- Erin K. Hickey
- Haiying Qin
- Hamilton O. Smith
- J. Craig
- Jeremy D. Peterson
- Jessica J. Vamathevan
- John F. Heidelberg
- Jonathan A. Eisen
- Karen A. Ketchum
- Karen E. Nelson
- Kelly S. Moffat
- Kenneth W. Minton
- Kira S. Makarova
- L. Aravind
- Lingxia Jiang
- Lisa Mcdonald
- Marie Crosby
- Mian Shen
- Michael J. Daly
- Michelle L. Gwinn
- Owen White
- Peter Lam
- Robert D. Fleischmann
- Robert J. Dodson
- Steven Salzberg
- Terry Utterback
- Venter
- Wanda Pamphile
- William C. Nelson
Organizations
- J. Craig Venter Institute
- Uniformed Services University of the Health Sciences
- United States National Library of Medicine