Genes, circuits, and precision therapies for autism and related neurodevelopmental disorders

Abstract

When the brain does not develop normally, the disabilities that ensue can affect a person for life. Sahin and Sur review how emerging knowledge of the molecular biology behind a suite of neurodevelopmental disorders is shedding light on the group as a whole. The new knowledge offers tantalizing leads toward more effective therapies.

Document Details

Document Type
Pub Defense Publication
Publication Date
Nov 20, 2015
Source ID
10.1126/science.aab3897

Entities

People

  • Mriganka Sur
  • Mustafa Şahin

Organizations

  • Autism Speaks
  • Boston Children's Hospital
  • Massachusetts Institute of Technology
  • Nancy Lurie Marks Family Foundation
  • National Institutes of Health
  • National Science Foundation
  • Novartis
  • Shire plc
  • Simons Foundation
  • Tuberous Sclerosis Alliance
  • United States Department of Defense

Tags

Readers

  • Child and Adolescent Substance Abuse Science in Autism Spectrum Disorders.
  • Marksmanship and Weaponry.
  • Systems Analysis and Design