A method for single-neuron chronic recording from the retina in awake mice
Abstract
Organisms take up a tremendous amount of information through the visual system, which is then processed by the neural circuitry. Hong et al. developed a mesh electronics implant that is delivered by injection into mice retinas. With these devices, it is possible to obtain recordings from retinal ganglion cells over long time periods in awake, active mice. Both orientation- and direction-selective retinal ganglion cells can be monitored, as can the circadian modulation of retinal ganglion cell activity.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jun 29, 2018
- Source ID
- 10.1126/science.aas9160
Entities
People
- Charles M. Lieber
- Guosong Hong
- Hong-Gyu Park
- Joshua R. Sanes
- Jung Min Lee
- Mu Qiao
- Robert D. Viveros
- Tao Zhou
- Tian-ming Fu
- Xiao Yang
Organizations
- Air Force Office of Scientific Research
- American Heart Association
- Blueprint for Neuroscience Research
- Harvard University
- Korea University
- National Institute on Aging
- Office of the Director