An ingestible bacterial-electronic system to monitor gastrointestinal health
Abstract
Bacteria are environmentally resilient and can be engineered to sense various biomolecules. Mimee et al. combined biosensor bacteria with a miniaturized wireless readout capsule to produce a minimally invasive device capable of in vivo biosensing in harsh, difficult-to-access environments (see the Perspective by Gibson and Burgell). The device successfully measured gastrointestinal bleeding in pigs.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- May 25, 2018
- Source ID
- 10.1126/science.aas9315
Entities
People
- Alison Hayward
- Anantha P. Chandrakasan
- Giovanni Traverso
- Joy Collins
- Logan Jerger
- Mark Mimee
- Phillip Nadeau
- Richard Swartwout
- Robert Citorik
- Robert S. Langer, Jr.
- Sarah Flanagan
- Sean Carim
- Shane McDonnell
- Timothy K. Lu
- Vladimir Bulovic
Organizations
- Brigham and Women's Hospital
- Harvard Medical School
- Innovation and Technology Commission
- Massachusetts General Hospital
- Massachusetts Institute of Technology
- National Institutes of Health
- National Science Foundation
- Office of Naval Research Global