The cysteinyl leukotriene 3 receptor regulates expansion of IL-25–producing airway brush cells leading to type 2 inflammation

Abstract

The leukotriene E 4 receptor, CysLT 3 R, regulates allergen-elicited expansion of airway brush cells and type 2 inflammation.

Document Details

Document Type
Pub Defense Publication
Publication Date
Oct 26, 2018
Source ID
10.1126/sciimmunol.aat9453

Entities

People

  • Daniel F Dwyer
  • Eri Yoshimoto
  • Hannah Raff
  • Jakob von Moltke
  • John W. Mcginty
  • K. Frank Austen
  • Lora G Bankova
  • Nora A Barrett
  • Saltanat Ualiyeva
  • Yoshihide Kanaoka

Organizations

  • Harvard Medical School
  • National Heart, Lung, and Blood Institute
  • National Institute of Allergy and Infectious Diseases
  • United States Department of Defense
  • University of Washington

Tags

Fields of Study

  • Medicine

Readers

  • Molecular and Cellular Biology
  • Neurological Diseases/Conditions/Disorders