Airway brush cells generate cysteinyl leukotrienes through the ATP sensor P2Y2

Abstract

Aeroallergens and ATP elicit cysteinyl leukotrienes from nasal brush cells through the purinergic receptor P2Y2.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 03, 2020
Source ID
10.1126/sciimmunol.aax7224

Entities

People

  • Carola Ledderose
  • Ichiro Matsumoto
  • Lora G Bankova
  • Nils Hallen
  • Nora A Barrett
  • Saltanat Ualiyeva
  • Wolfgang G. Junger
  • Yoshihide Kanaoka

Organizations

  • American Academy of Allergy, Asthma, and Immunology
  • American Lung Association
  • Eunice Kennedy Shriver National Institute of Child Health and Human Development
  • Harvard Medical School
  • Monell Chemical Senses Center
  • National Heart, Lung, and Blood Institute
  • National Institute of Allergy and Infectious Diseases
  • National Institute on Deafness and Other Communication Disorders
  • United States Department of Defense