Targeting Piezo1 unleashes innate immunity against cancer and infectious disease
Abstract
Blockade of the Piezo1 mechanoreceptor decreases myeloid cell suppression of immune responses to cancer and polymicrobial sepsis.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Aug 14, 2020
- Source ID
- 10.1126/sciimmunol.abb5168
Entities
People
- Alireza Khodadadi-Jamayran
- Anjana Saxena
- Berk Aykut
- Brian Diskin
- Deepak Saxena
- Dongling Wu
- George Miller
- Gregor Werba
- Jacqueline I. Kim
- Joshua Leinwand
- Matthew Berman
- Pamela Preiss
- Raquel Abengozar
- Ruonan Chen
- Smruti Pushalkar
- Sorin A. A. Shadaloey
- Steve Ki Buom Lee
- Wei Wang
- William A. Coetzee
Organizations
- Brooklyn College
- CUNY Graduate School and University Center
- Damon Runyon Cancer Research Foundation
- German Research Foundation
- Grossman School of Medicine
- Mary Kay Foundation
- National Institutes of Health
- National Science Foundation
- New York University
- New York University College of Dentistry
- United States Department of Defense
- V Foundation for Cancer Research