T Cell Receptor Signals to NF-κB Are Transmitted by a Cytosolic p62-Bcl10-Malt1-IKK Signalosome

Abstract

Assembly of a multiprotein complex containing the adaptor protein p62 promotes NF-κB activation in T cells.

Document Details

• Document Type: Pub Defense Publication
• Publication Date: May 13, 2014
• Source ID: 10.1126/scisignal.2004882

Entities

People

• Anuj K. Kashyap
• Brian C. Schaefer
• Joseph R. Latoche
• Maria Traver
• Michael A. Washington
• Suman Paul

Organizations

• Uniformed Services University of the Health Sciences