A biosensor for the activity of the “sheddase” TACE (ADAM17) reveals novel and cell type–specific mechanisms of TACE activation
Abstract
A FRET-based sensor reports the spatiotemporal dynamics of the protease TACE in live cells.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Feb 24, 2015
- Source ID
- 10.1126/scisignal.2005680
Entities
People
- Douglas A. Chapnick
- Eric Bunker
- Xuedong Liu
Organizations
- Defense Advanced Research Projects Agency
- National Center for Research Resources
- National Institutes of Health
- University of Colorado