The transcription factor ATF2 promotes melanoma metastasis by suppressing protein fucosylation
Abstract
Suppressing ATF2 or supplementing the diet with fucose impairs growth and metastasis of melanoma in mice.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Dec 08, 2015
- Source ID
- 10.1126/scisignal.aac6479
Entities
People
- Ally Perlina
- Dylan Donn
- Eric Lau
- Giuseppina Claps
- Harriet Kluger
- Hudson H. Freeze
- Lucia Jilaveanu
- Michiko N. Fukuda
- Yongmei Feng
- Ze'ev A. Ronai
Organizations
- Hervey Foundation
- Melanoma Research Foundation
- National Cancer Institute
- National Institutes of Health
- Sanford Burnham Prebys Medical Discovery Institute
- Yale University