Mystery solved: Trehalose kickstarts autophagy by blocking glucose transport

Abstract

Trehalose may be a silver bullet in the therapeutic arsenal against proteostasis and metabolic disorders.

Document Details

Document Type
Pub Defense Publication
Publication Date
Feb 23, 2016
Source ID
10.1126/scisignal.aaf1937

Entities

People

  • Claudio Hetz
  • David C. Rubinsztein
  • Pablo Mardones

Organizations

  • ALS Therapy Alliance
  • CONICYT
  • Harvard T.H. Chan School of Public Health
  • Millennium Institute
  • Muscular Dystrophy Association
  • National Fund for Scientific and Technological Development
  • National Institute for Health and Care Research
  • Office of Naval Research Global
  • The Michael J. Fox Foundation
  • University of Cambridge
  • Wellcome Trust

Tags

Fields of Study

  • Chemistry