Pentraxin-3 is a PI3K signaling target that promotes stem cell–like traits in basal-like breast cancers

Abstract

PI3K-stimulated induction of pentraxin-3 links innate immune signaling with the growth of basal-like breast cancer.

Document Details

Document Type
Pub Defense Publication
Publication Date
Feb 21, 2017
Source ID
10.1126/scisignal.aah4674

Entities

People

  • Albert S Baldwin
  • Alex Toker
  • Anne Vincent-salomon
  • Anthony Y. Collmann
  • Antoine E Karnoub
  • Benjamin G Cuiffo
  • Charles M. Perou
  • Cheng Fan
  • Clémence Thomas
  • Elisabetta Marangoni
  • Laetitia Fuhrmann
  • Manoj K. Bhasin
  • Vanessa Benhamo
  • Whitney Henry

Organizations

  • Curie Institute
  • Harvard Medical School
  • Harvard Stem Cell Institute
  • National Institutes of Health
  • Susan G. Komen for the Cure
  • United States Department of Defense
  • University of North Carolina at Chapel Hill

Tags

Readers

  • Immunology
  • Molecular Biology and Genetics
  • Nuclear Non-Proliferation and International Security

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech