An interspecies translation model implicates integrin signaling in infliximab-resistant inflammatory bowel disease
Abstract
A platform for comparing trans-omics datasets between IBD mouse models and human patients reveals therapeutically relevant targets.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Aug 04, 2020
- Source ID
- 10.1126/scisignal.aay3258
Entities
People
- Alan J Simmons
- Alina Starchenko
- Austin N. Southard-Smith
- Cecil Gregg
- Douglas A. Lauffenburger
- Douglas K Brubaker
- Elizabeth A. Scoville
- Evan L Chiswick
- Keith T. Wilson
- Ken S. Lau
- Lori A. Coburn
- Manu P. Kumar
- Paige N Vega
Organizations
- Army Research Office
- Boehringer Ingelheim
- Leona M. and Harry B. Helmsley Charitable Trust
- Massachusetts Institute of Technology
- National Institute of Diabetes and Digestive and Kidney Diseases
- National Institutes of Health
- Purdue University
- Vanderbilt University
- Vanderbilt University Medical Center