Mitochondrial pyruvate and fatty acid flux modulate MICU1-dependent control of MCU activity
Abstract
Nutrient stress triggers transcriptional changes that limit Ca 2+ influx into mitochondria through the MCU.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Apr 21, 2020
- Source ID
- 10.1126/scisignal.aaz6206
Entities
People
- Benjamin T Enslow
- Brij B Singh
- Cassidy C Daw
- Cherubina S Rubannelsonkumar
- Chris Shannon
- Jonathan Soboloff
- Kalimuthusamy Natarajanseenivasan
- Karthik Ramachandran
- Kumar Sharma
- Luke Norton
- Muniswamy Madesh
- Neeharika Nemani
- Pragya Singhmalla
- Robert Hooper
- Santhanam Shanmughapriya
- Soumya Maity
- Subramanya Srikantan
- Travis R Madaris
- Varshini Mallireddigari
- Warren G. Tourtellotte
- William Reeves
- Zhiwei Dong
Organizations
- Cedars-Sinai Medical Center
- Office of the Director
- Temple University