Decade-Long Safety and Function of Retroviral-Modified Chimeric Antigen Receptor T Cells

Abstract

Adoptively transferred chimeric antigen receptor T cells have stable stem cell–like persistence for at least a decade and more than 500 years of patient safety.

Document Details

Document Type
Pub Defense Publication
Publication Date
May 02, 2012
Source ID
10.1126/scitranslmed.3003761

Entities

People

  • Ashley N. Vogel
  • Bruce L. Levine
  • Carl H. June
  • Frederic D. Bushman
  • Gabriela Plesa
  • Gwendolyn Binder-scholl
  • James L. Riley
  • John Scholler
  • Kristen M. Hege
  • Michael Kalos
  • Naomi E. Aronson
  • Ronald T. Mitsuyasu
  • Steven G Deeks
  • Troy L. Brady
  • Wei-ting Hwang
  • Wendy B. Bernstein

Organizations

  • Celgene
  • Uniformed Services University of the Health Sciences
  • University of California, Los Angeles
  • University of California, San Francisco
  • University of Pennsylvania
  • Walter Reed National Military Medical Center

Tags

Fields of Study

  • Biology

Readers

  • Breast cancer cell signaling and growth regulation.
  • Immunology
  • Systems Analysis and Design

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech