Treatment of heterotopic ossification through remote ATP hydrolysis

Abstract

Heterotopic ossification induced by injuries and burns is mediated by signaling through the SMAD pathway and can be targeted with topical apyrase.

Document Details

Document Type
Pub Defense Publication
Publication Date
Sep 24, 2014
Source ID
10.1126/scitranslmed.3008810

Entities

People

  • Benjamin Lévi
  • Chuanwu Xi
  • David N. Herndon
  • Jonathan R. Peterson
  • Katherine E. Cilwa
  • Michael D. Morris
  • Oluwatobi Eboda
  • Paul H. Krebsbach
  • Paul S Cederna
  • Ronald G. Tompkins
  • Sara De La Rosa
  • Shailesh Agarwal
  • Steven R. Buchman
  • Stewart C. Wang
  • Wenzhong Xiao

Organizations

  • Massachusetts General Hospital
  • Naval Medical Research Center
  • University of Michigan
  • University of Texas Medical Branch

Tags

Fields of Study

  • Chemistry