Rational design of small molecules as vaccine adjuvants
Abstract
Small-molecule immune potentiators can be engineered to be potent adjuvants with localized innate immune activation and short in vivo residence times.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Nov 19, 2014
- Source ID
- 10.1126/scitranslmed.3009980
Entities
People
- Alex Cortez
- Andrew T. Miller
- Ann E. Herman
- Bishnu P. Nayak
- Brunella Brunelli
- Christophe M. Filippi
- Chun Li
- David A. G. Skibinski
- Derek T. O'hagan
- Donatello Laera
- Elaine Tritto
- Elena Caproni
- Elisabetta Monaci
- Ennio De Gregorio
- Francesco Doro
- Gillis R. Otten
- Luis A. Brito
- M. Lamine Mbow
- Manmohan Singh
- Michael P. Cooke
- Nicholas M. Valiante
- Padma Malyala
- Rekha G. Panchal
- Samuele Calabrό
- Sara Valentini
- Simone Bufali
- Sina Bavari
- Susanna Aprea
- Tom Y.-h. Wu
- Travis K. Warren
- Ugo D’oro
- Yongkai Li
Organizations
- United States Army Medical Research Institute of Infectious Diseases