Regulation of immune responses to protein therapeutics by transplacental induction of T cell tolerance
Abstract
Transplacental modulation of T cell repertoire during immune ontogeny leads to antigen-specific immune tolerance to an immunogenic protein therapeutic.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Feb 18, 2015
- Source ID
- 10.1126/scitranslmed.aaa1957
Entities
People
- Bagirath Gangadharan
- Benoit L. Salomon
- Christophe Arnoult
- David W Scott
- Jordan Dimitrov
- Maxime Lecerf
- Nimesh Gupta
- Roberto Mallone
- Sandrine Delignat
- Slobodan Culina
- Srinivas V. Kaveri
- Sune Justesen
- Sébastien Lacroix-desmazes
- Valérie Gouilleux-gruart
- Yann Meslier
Organizations
- Agence Nationale de la Recherche
- Assistance Publique – Hôpitaux de Paris
- Centre de Recherche des Cordeliers
- European Foundation for the Study of Diabetes
- French National Institute of Health and Medical Research
- Hôpital Cochin
- JDRF
- National Center for Scientific Research
- Novo Nordisk UK Research Foundation
- Paris Descartes University
- Pierre and Marie Curie University
- Sorbonne Universités
- Uniformed Services University of the Health Sciences
- University of Copenhagen