Active targeting of chemotherapy to disseminated tumors using nanoparticle-carrying T cells
Abstract
Nanoparticle-functionalized T cells actively transport a cytotoxic drug to systemic sites of lymphoma dissemination, enhancing the efficacy of antitumor chemotherapy.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jun 10, 2015
- Source ID
- 10.1126/scitranslmed.aaa5447
Entities
People
- Bonnie Huang
- Darrell J Irvine
- Samantha S. Luo
- Sandra C. Bustamante López
- Wuhbet D. Abraham
- Yiran Zheng
Organizations
- Howard Hughes Medical Institute
- Koch Institute for Integrative Cancer Research at MIT
- Massachusetts General Hospital
- Massachusetts Institute of Technology
- National Cancer Institute
- National Institutes of Health
- United States Department of Defense