Prefusion F–specific antibodies determine the magnitude of RSV neutralizing activity in human sera

Abstract

Antibodies to the prefusion conformation of the RSV F glycoprotein neutralize natural infection.

Document Details

Document Type
Pub Defense Publication
Publication Date
Oct 14, 2015
Source ID
10.1126/scitranslmed.aac4241

Entities

People

  • Aliaksandr Druz
  • April M. Killikelly
  • Azad Kumar
  • Baoshan Zhang
  • Barney S. Graham
  • Cristina Capella
  • Emily J. Rundlet
  • Guillaume B. E. Stewart-jones
  • Gwo-yu Chuang
  • Hadi M. Yassine
  • Ivelin S. Georgiev
  • Jason S. McLellan
  • Joan O. Ngwuta
  • Julie E. Ledgerwood
  • Kayvon Modjarrad
  • M Gordon Joyce
  • Mallika Sastry
  • Man Chen
  • Mark E. Peeples
  • Martha C. Nason
  • Masaru Kanekiyo
  • Peter D. Kwong
  • Syed M. Moin
  • Yongping Yang

Organizations

  • Geisel School of Medicine
  • National Institutes of Health
  • Ohio State University
  • United States Military HIV Research Program

Tags

Fields of Study

  • Biology