NS1: A corner piece in the dengue pathogenesis puzzle?

Abstract

Dengue virus NS1 protein induces inflammation via Toll-like receptor 4 and disrupts endothelial cell integrity to cause vascular leakage (Beatty et al . and Modhiran et al ., this issue).

Document Details

Document Type
Pub Defense Publication
Publication Date
Sep 09, 2015
Source ID
10.1126/scitranslmed.aad1255

Entities

People

  • Stephen J Thomas

Organizations

  • Walter Reed Army Institute of Research

Tags

Readers

  • Immunology and Pathology
  • Military History
  • Virology (or Medical Virology).