PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: Mechanisms, response biomarkers, and combinations

Abstract

PD pathway blockade elicits durable antitumor responses in a subset of patients with a broad spectrum of cancers.

Document Details

Document Type
Pub Defense Publication
Publication Date
Mar 02, 2016
Source ID
10.1126/scitranslmed.aad7118

Entities

People

  • Jedd D. Wolchok
  • Lieping Chen
  • Weiping Zou

Organizations

  • Harry J. Lloyd Charitable Trust
  • Memorial Sloan Kettering Cancer Center
  • National Institutes of Health
  • Ovarian Cancer Research Alliance
  • Stand Up to Cancer
  • United States Department of Defense
  • University of Michigan
  • Yale University

Tags

Fields of Study

  • Psychology

Readers

  • Immunology and Pathology
  • Oncology