Complete attenuation of genetically engineered Plasmodium falciparum sporozoites in human subjects
Abstract
A genetically attenuated Plasmodium falciparum strain called Pf GAP3KO is completely attenuated, safe, and immunogenic in adults.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 04, 2017
- Source ID
- 10.1126/scitranslmed.aad9099
Entities
People
- Annette Seilie
- Ashley M. Vaughan
- Brandon K. Sack
- D. Noah Sather
- Dorender A. Dankwa
- Emma Fritzen
- Heather S. Kain
- James G. Kublin
- Lisa Shelton
- Matt E. Fishbaugher
- Melike Firat
- Ryan W. J. Steel
- Sara Magee
- Sean C. Murphy
- Sebastian A. Mikolajczak
- Stefan H I Kappe
- Tracie Vongoedert
- Will Betz
Organizations
- Center for Infectious Disease Research
- Fred Hutchinson Cancer Center
- Gates Foundation
- University of Washington