Obesity promotes resistance to anti-VEGF therapy in breast cancer by up-regulating IL-6 and potentially FGF-2
Abstract
Targeting IL-6 and potentially FGF-2 overcomes resistance to anti-VEGF therapy in breast cancer.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Mar 14, 2018
- Source ID
- 10.1126/scitranslmed.aag0945
Entities
People
- Christopher L. Schlett
- Dai Fukumura
- Dan G Duda
- Daniel T. Mcmanus
- Dannie Wang
- Ian E. Krop
- Igor L Gomes-Santos
- Jennifer A. Ligibel
- Joao Incio
- Keehoon Jung
- Kosuke Kawaguchi
- Marek Ancukiewicz
- Matthias Pinter
- Nuh N. Rahbari
- Priya Suboj
- Rakesh Jain
- Sara M Tolaney
- Shan M Chin
- Stefan B. Puchner
- Suboj Babykutty
- Sylvie Roberge
- Trupti D. Vardam
- Udo Hoffmman
- Yuhui Huang
- Yves Boucher
Organizations
- Fundação para a Ciência e Tecnologia
- Harvard Medical School
- Mar Ivanios College
- Medical University of Vienna
- National Cancer Institute
- St. Xavier's College, Mumbai
- São Paulo Research Foundation
- United States Department of Defense
- University of Porto
- University of São Paulo