Delayed differentiation of potent effector CD8 + T cells reducing viremia and reservoir seeding in acute HIV infection
Abstract
Potent CD8 + T cells endowed with effector functions able to kill HIV-producing cells and reduce the seeding of the HIV reservoir are only detected at peak viremia in acute HIV infection.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Feb 15, 2017
- Source ID
- 10.1126/scitranslmed.aag1809
Entities
People
- Cari Kessing
- Carmen N. Nichols
- Claire Vandergeeten
- Elias K Haddad
- Eugène Kroon
- Hiroshi Takata
- James L. K. Fletcher
- Jerome H Kim
- Jintanat Ananworanich
- Lydie Trautmann
- Merlin L Robb
- Nelson Michael
- Nicolas Chomont
- Nittaya Phanuphak
- On Behalf Of The Rv254/search010 And The Rv304/search013 Study Groups
- Pearline Cartwright
- Pokrath Hansasuta
- Robert O’connell
- Roshell Muir
- Supranee Buranapraditkun
- Suteeraporn Pinyakorn
- Thep Chalermchai
- Virginie Tardif
- Wendy Bakeman
Organizations
- Armed Forces Research Institute of Medical Sciences
- Case Western Reserve University
- Chulalongkorn University
- Drexel University
- Henry M. Jackson Foundation for the Advancement of Military Medicine
- International Vaccine Institute
- National Institute of Allergy and Infectious Diseases
- Scripps Research
- Thai Red Cross Society
- United States Department of Defense
- United States Military HIV Research Program
- University of Oxford
- Université de Montréal