RON kinase: A target for treatment of cancer-induced bone destruction and osteoporosis

Abstract

Inhibition of RON kinase prevents pathogenic bone destruction in mouse models and in a first-in-human clinical study.

Document Details

• Document Type: Pub Defense Publication
• Publication Date: Jan 25, 2017
• Source ID: 10.1126/scitranslmed.aai9338

Entities

People

• Alana L Welm
• Jaime Fornetti
• Kelsi Andrade
• Ling Zhao
• Mark Mchale
• Neysi Anderson
• R. Lor Randall
• Scott C. Miller
• Susan E. Waltz

Organizations

• National Cancer Institute
• Oklahoma Medical Research Foundation
• Susan G. Komen for the Cure
• United States Department of Defense
• University of Cincinnati
• University of Utah