Targeting mitochondrial responses to intra-articular fracture to prevent posttraumatic osteoarthritis

Abstract

Inhibiting mitochondrial oxidant production after surgical fixation of an intra-articular fracture prevents osteoarthritis in a porcine model.

Document Details

Document Type
Pub Defense Publication
Publication Date
Feb 07, 2018
Source ID
10.1126/scitranslmed.aan5372

Entities

People

  • Aliasger Salem
  • Angie S Morris
  • Behnoush Khorsand
  • Dongrim Seol
  • Douglas C Fredericks
  • Emily B Petersen
  • Hope D. Anderson
  • James Martin
  • Jessica E Goetz
  • Jocelyn T Compton
  • Marc J Brouillette
  • Michael C. Willey
  • Mitchell C Coleman
  • Nathan R. Hendrickson
  • Todd O McKinley

Organizations

  • Indiana University
  • National Institutes of Health Clinical Center
  • United States Department of Defense
  • University of Iowa
  • Wellesley College

Tags

Fields of Study

  • Medicine