Development of a stress response therapy targeting aggressive prostate cancer
Abstract
The PERK-eIF2α pathway is activated in aggressive prostate cancer and associated with patient outcome, providing a therapeutic target for the disease.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- May 02, 2018
- Source ID
- 10.1126/scitranslmed.aar2036
Entities
People
- Andrew C Hsieh
- Byron Hann
- Charles Truillet
- Christopher P Evans
- Costas Koumenis
- Craig M Forester
- Crystal S Conn
- Davide Ruggero
- Feven Tameire
- Hao G. Nguyen
- Janet E Cowan
- John T Cunningham
- Joy C. Yang
- Lingru Xue
- Michael J Evans
- Peter R. Carroll
- Peter Walter
- Yae Kye
Organizations
- American Cancer Society
- National Institutes of Health
- Prostate Cancer Foundation
- United States Department of Defense
- University of California, Davis, School of Medicine
- University of California, San Francisco
- University of Pennsylvania
- Urology Care Foundation