A biologic scaffold–associated type 2 immune microenvironment inhibits tumor formation and synergizes with checkpoint immunotherapy
Abstract
Biologic scaffolds synergize with immune checkpoint blockade to inhibit tumor growth in mice in a process requiring T cells and macrophages.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 30, 2019
- Source ID
- 10.1126/scitranslmed.aat7973
Entities
People
- Alexis J Parrillo
- Benjamin V. Park
- Christopher Cherry
- Christopher W Anderson
- Drew M Pardoll
- Fan Pan
- Guannan Wang
- Jennifer Elisseeff
- Kaitlyn Sadtler
- Matthew T Wolf
- Radhika Narain
- Saraswati Sukumar
- Sudipto Ganguly
- Tony L. Wang
Organizations
- Bloomberg L.P.
- Hartwell Foundation
- Harvard Medical School
- Johns Hopkins University
- Massachusetts Institute of Technology
- Melanoma Research Alliance
- National Cancer Institute
- National Institutes of Health
- United States Department of Defense
- University of Illinois College of Medicine
- Yale University