Cartilage-penetrating nanocarriers improve delivery and efficacy of growth factor treatment of osteoarthritis

Abstract

A charged molecular carrier enables sustained growth factor delivery to cartilage, demonstrating therapeutic benefit in a rat model of osteoarthritis.

Document Details

Document Type
Pub Defense Publication
Publication Date
Nov 28, 2018
Source ID
10.1126/scitranslmed.aat8800

Entities

People

  • Alan J. Grodzinsky
  • Brett Geiger
  • Paula T. Hammond
  • Robert F Padera
  • Sheryl Wang

Organizations

  • Harvard Medical School
  • Koch Institute for Integrative Cancer Research at MIT
  • Massachusetts Institute of Technology
  • United States Department of Defense

Tags

Fields of Study

  • Medicine

Readers

  • Nanocomposite Materials Science
  • Neurotrauma and Rehabilitation Medicine.