Platelet decoys inhibit thrombosis and prevent metastatic tumor formation in preclinical models

Abstract

Human platelet decoys prevented thrombosis in rabbits and inhibited cancer cell aggregation and extravasation in vitro and in a mouse model.

Document Details

Document Type
Pub Defense Publication
Publication Date
Feb 13, 2019
Source ID
10.1126/scitranslmed.aau5898

Entities

People

  • Abhishek Jain
  • Akiko Mammoto
  • Amanda Graveline
  • Amanda Jiang
  • Andyna Vernet
  • Anna Waterhouse
  • Anne-Laure Papa
  • Donald E. Ingber
  • Emma Nash
  • Erin T Langan
  • Jildaz Caroff
  • Matthew J Gounis
  • Michelle B. Chen
  • Natanel Korin
  • R D Kamm
  • Tadanori Mammoto

Organizations

  • George Washington University
  • Harvard Medical School
  • Harvard University
  • Massachusetts Institute of Technology
  • National Institutes of Health
  • United States Department of Defense
  • University of Massachusetts

Tags

Fields of Study

  • Biology
  • Chemistry
  • Medicine

Readers

  • Immunology and Pathology
  • Oncology (Cancer Research).