An antibody-drug conjugate directed to the ALK receptor demonstrates efficacy in preclinical models of neuroblastoma

Abstract

ALK is a tractable antibody-drug conjugate target in neuroblastoma.

Document Details

Document Type
Pub Defense Publication
Publication Date
Mar 13, 2019
Source ID
10.1126/scitranslmed.aau9732

Entities

People

  • Bruce Pawel
  • Colleen E. Larmour
  • Daniel Martinez
  • Diego Alvarado
  • Gwenda F. Ligon
  • Jay S. Lillquist
  • Kateryna Krytska
  • Paolo Orsini
  • Pichai Raman
  • Renata Sano
  • Simona Rizzi
  • Ulisse Cucchi
  • Yael P. Mossé

Organizations

  • Children's Hospital of Philadelphia
  • United States Department of Defense
  • University of Pennsylvania

Tags

Fields of Study

  • Biology
  • Medicine