Increased soluble TREM2 in cerebrospinal fluid is associated with reduced cognitive and clinical decline in Alzheimer’s disease
Abstract
Higher CSF sTREM2 concentrations are associated with slower rates of cognitive decline in subjects with Alzheimer’s disease.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Aug 28, 2019
- Source ID
- 10.1126/scitranslmed.aav6221
Entities
People
- Carlos Cruchaga
- Christian Haass
- Estrella Morenas-rodriguez
- Gernot Kleinberger
- John Q. Trojanowski
- Laura Piccio
- Leslie M. Shaw
- Marc Suárez-Calvet
- Martin Dichgans
- Michael Ewers
- Michael W. Weiner
- Miguel Angel Araque Caballero
- Nicolai Franzmeier
- The Alzheimer’s Disease Neuroimaging Initiative*
- Yuetiva Deming
Organizations
- Autonomous University of Barcelona
- Cure Alzheimer's Fund
- German Center for Neurodegenerative Diseases
- German Research Foundation
- Hospital del Mar
- Ludwig-Maximilians-Universität München
- Munich Cluster for Systems Neurology
- National Institutes of Health
- Pasqual Maragall Foundation
- United States Department of Defense
- University of California, San Francisco
- University of Pennsylvania
- University of Sydney
- Washington University in St. Louis