A vaccine-induced gene expression signature correlates with protection against SIV and HIV in multiple trials

Abstract

A gene signature in B cells associates with protective efficacy of different vaccine regimens against SIV and HIV infection.

Document Details

Document Type
Pub Defense Publication
Publication Date
Aug 28, 2019
Source ID
10.1126/scitranslmed.aaw4236

Entities

People

  • Aviva Geretz
  • Biju Issac
  • Christopher Bryant
  • Dan H. Barouch
  • Diane L Bolton
  • Frank Wegmann
  • Galit Alter
  • H Schuitemaker
  • Maria G Pau
  • Matthew Creegan
  • Merlin L Robb
  • Michael A Eller
  • Nelson Michael
  • Philip K. Ehrenberg
  • Rafick-Pierre Sékaly
  • Rasmi Thomas
  • Richard Apps
  • Robert A Gramzinski
  • Shida Shangguan
  • Taisuke Izumi

Organizations

  • Case Western Reserve University
  • Emmes Corporation
  • Harvard Medical School
  • Henry M. Jackson Foundation for the Advancement of Military Medicine
  • Janssen Vaccines
  • Massachusetts General Hospital
  • National Institute of Allergy and Infectious Diseases
  • National Institutes of Health
  • Walter Reed Army Institute of Research

Tags

Fields of Study

  • Biology
  • Mathematics

Readers

  • Immunology
  • Sensor Fusion and Tracking Systems.

Technology Areas

  • Biotechnology