Engineered probiotics for local tumor delivery of checkpoint blockade nanobodies

Abstract

An engineered probiotic system locally delivers checkpoint blockade nanobodies to tumors for sustained therapeutic release.

Document Details

• Document Type: Pub Defense Publication
• Publication Date: Feb 12, 2020
• Source ID: 10.1126/scitranslmed.aax0876

Entities

People

• Candice R Gurbatri
• Courtney Coker
• Ioana Lia
• Nicholas Arpaia
• Piper M Treuting
• Rosa Vincent
• Samuel Castro
• Tal Danino
• Taylor E. Hinchliffe

Organizations

• Columbia University
• Columbia University Vagelos College of Physicians and Surgeons
• National Science Foundation
• Office of the Director
• The Breast Cancer Research Foundation
• United States Department of Defense
• University of Washington