Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia

Abstract

A next-generation, broad-spectrum, orally efficacious influenza A and B virus inhibitor is associated with a high genetic resistance barrier.

Document Details

Document Type
Pub Defense Publication
Publication Date
Oct 23, 2019
Source ID
10.1126/scitranslmed.aax5866

Entities

People

  • Alec H Barrena
  • Alexander A. Kolykhalov
  • Alexander L. Greninger
  • Deborah G. Mitchell
  • George R. Painter
  • Gregory R Bluemling
  • Jeong-Joong Yoon
  • Mart Toots
  • Michael G. Natchus
  • Michael Hart
  • Negar Makhsous
  • Prabhakar G. Reddy
  • Richard K Plemper
  • Robert M. Cox
  • Roland Plesker
  • Ryan C Shean
  • Zachary M Sticher

Organizations

  • Defense Threat Reduction Agency
  • Emory University
  • Eunice Kennedy Shriver National Institute of Child Health and Human Development
  • Georgia State University
  • National Institute of Allergy and Infectious Diseases
  • Paul Ehrlich Institute
  • University of Washington

Tags

Readers

  • Immunology
  • Immunology and Pathology
  • Molecular Genetics

Technology Areas

  • Biotechnology