Engraftment of rare, pathogenic donor hematopoietic mutations in unrelated hematopoietic stem cell transplantation

Abstract

Donor hematopoietic clones with pathogenic mutations engraft and persist in unrelated hematopoietic stem cell transplant recipients.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 15, 2020
Source ID
10.1126/scitranslmed.aax6249

Entities

People

  • Amelia Bystry
  • Bronwen E Shaw
  • Dennis L Confer
  • Fei Wan
  • Galen E Switzer
  • Iskra Pusic
  • Jamie R Blundell
  • Jennifer Sees
  • John DiPersio
  • Kathryn Trinkaus
  • Kevin Elliott
  • Michael A Pulsipher
  • Nirali N. Shah
  • Nitin Mahajan
  • Sima Bhatt
  • Todd E Druley
  • Wing H Wong

Organizations

  • Center for International Blood and Marrow Transplant Research
  • Health Resources and Services Administration
  • Hyundai Hope On Wheels
  • Leukemia & Lymphoma Society
  • Medical College of Wisconsin
  • National Cancer Institute
  • National Heart, Lung, and Blood Institute
  • Office of Naval Research
  • University of Cambridge
  • University of Pittsburgh
  • University of Southern California
  • Washington University School of Medicine

Tags

Fields of Study

  • Medicine

Readers

  • Immunology and Pathology
  • Molecular and genetic basis of cancer.

Technology Areas

  • Biotechnology