Gene therapy delivering a paraoxonase 1 variant offers long-term prophylactic protection against nerve agents in mice

Abstract

Paraoxonase 1 variant IF-11 offers long-term prophylactic protection against chemical warfare nerve agents in mice.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 22, 2020
Source ID
10.1126/scitranslmed.aay0356

Entities

People

  • Deborah M. Doctor
  • Liliya Silayeva
  • Nageswararao Chilukuri
  • Reena Goswami
  • Venkaiah Betapudi

Organizations

  • Defense Threat Reduction Agency

Tags

Fields of Study

  • Biology
  • Medicine

Readers

  • Molecular Genetics
  • Neurotoxicology

Technology Areas

  • Biotechnology