Blockade of immune checkpoints in lymph nodes through locoregional delivery augments cancer immunotherapy

Abstract

Anticancer therapeutic effects can be improved by directing immune checkpoint blockade antibodies to tumor-draining lymph nodes.

Document Details

Document Type
Pub Defense Publication
Publication Date
Sep 30, 2020
Source ID
10.1126/scitranslmed.aay3575

Entities

People

  • Alex Schudel
  • Brian P. Pollack
  • David M. Francis
  • Edmund K Waller
  • Haydn T. Kissick
  • Lauren F Sestito
  • Margaret P Manspeaker
  • Meghan J O'Melia
  • Susan N Thomas

Organizations

  • American Heart Association
  • Emory University
  • Georgia Tech
  • National Institutes of Health
  • National Science Foundation
  • Susan G. Komen for the Cure
  • United States Department of Defense

Tags

Fields of Study

  • Biology
  • Medicine

Readers

  • Immunology
  • Oncology (Cancer Research).

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech