An ultrafast insulin formulation enabled by high-throughput screening of engineered polymeric excipients
Abstract
Monomeric insulin stabilized with polymeric excipient exhibits increased stability and faster pharmacokinetics than current rapid-acting insulins.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jul 01, 2020
- Source ID
- 10.1126/scitranslmed.aba6676
Entities
People
- Abigail Grosskopf
- Almar Postma
- Anthony Yu
- Anton Allen Abbotsford Smith
- Benjamin W Muir
- Caitlin Maikawa
- Catherine M Meis
- Celine S Liong
- Doreen Chan
- Emily Gale
- Eric A Appel
- Gillie Agmon
- Joseph L Mann
- Lyndsay M Stapleton
- Sam W. Baker
- Santiago Correa
- Shaun C Howard
Organizations
- Aarhus University
- Commonwealth Scientific and Industrial Research Organisation
- National Institute of Diabetes and Digestive and Kidney Diseases
- Natural Sciences and Engineering Research Council
- Novo Nordisk Fonden
- Stanford University
- United States Department of Defense