Mapping functional humoral correlates of protection against malaria challenge following RTS,S/AS01 vaccination

Abstract

A combination of two Fc antibody features that leverage innate immune function predicts protection from malaria challenge after RTS,S/AS01 vaccination.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jul 22, 2020
Source ID
10.1126/scitranslmed.abb4757

Entities

People

  • Allison R Demas
  • Ashlin Michell
  • Caitlyn H Linde
  • Claudia P Arevalo
  • Corinne Luedemann
  • Douglas A. Lauffenburger
  • Elke S Bergmann-Leitner
  • Erik Jongert
  • Fidel Zavala
  • Galit Alter
  • Harini Natarajan
  • Jenny Hendriks
  • Jerald Sadoff
  • Jishnu Das
  • Jonathan Crain
  • Jonathan K Fallon
  • Joshua A Weiner
  • Margaret E. Ackerman
  • Margherita Coccia
  • Matthew Slein
  • Meghan Marquette
  • Richard Lu
  • Sandra March
  • Sangeeta N. Bhatia
  • Scott Gregory
  • Sheetij Dutta
  • Thomas Broge
  • Thomas Linnekin
  • Todd J Suscovich
  • Ulrike Wille-reece
  • Viraj Kulkarni
  • Yevel Flores-garcia

Organizations

  • Brigham and Women's Hospital
  • Broad Institute
  • Dartmouth College
  • GSK
  • Harvard University
  • Howard Hughes Medical Institute
  • Koch Institute for Integrative Cancer Research at MIT
  • Massachusetts General Hospital
  • Massachusetts Institute of Technology
  • PATH
  • Walter Reed Army Institute of Research

Tags

Readers

  • Immunology
  • Oncology
  • Parasitology and Pharmacology of Malaria.

Technology Areas

  • Biotechnology