A small-molecule activator of the unfolded protein response eradicates human breast tumors in mice
Abstract
Activation of the unfolded protein response induces regression of estrogen receptor α–positive breast cancer xenografts in mice.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jul 21, 2021
- Source ID
- 10.1126/scitranslmed.abf1383
Entities
People
- Ben Ho Park
- Bingtao Tang
- Chengjian Mao
- Darjan Duraki
- David J. Shapiro
- Edward Roy
- Elizabeth M. Bruckheimer
- Erik R Nelson
- Geoffrey L Greene
- Jeff Kiefer
- Ji Eun Kim
- Lawrence Wang
- Madeline A. Henn
- Matthew W Boudreau
- Paul J. Hergenrother
- Ramon Moreno
- Sean W Fanning
- Spyro Mousses
- Theodore M. Tarasow
- Timothy M Fan
Organizations
- National Institutes of Health
- United States Department of Defense
- University of Chicago
- University of Illinois Urbana–Champaign
- Vanderbilt University